Dr. Fuller's research group seeks to understand molecular mechanisms of how viruses enter cells and how they mediate events of membrane fusion and spread. They study the prevalent human pathogens, herpes simplex viruses (HSV) 1 and 2 and a closely related herpesvirus of porcine- pseudorabies viruses (PRV) and have begun several collaborative investigations with researchers in engineering or public health to develop microchip technology for detection of genetic changes in human pathogens such influenza virus, or to explore involvement of neurotropic viruses in dementia. These studies involve a broad range of approaches in molecular and cell biology, genetics, membrane biology, biochemistry and virology.