The affiliations listed below show engagement with the Graham Sustainability Institute.
- Education Programs
- Biomedical Engineering
- Chemical Engineering
Research in the Linderman group focuses on understanding the binding of extracellular ligands to cell surface receptors and the signal transduction events involved in the generation of a cellular response. Current work includes: (1) multi-scale and multi-system approaches to understanding the immune response to Mycobacterium tuberculosis, focusing especially on the role of TNF and IL-10, and (2) mathematical models of signal transduction, particularly for G-protein coupled receptors, and including complex membrane geometries.